報告書番号

482021

タイトル（和文）

電界が実験動物の行動に及ぼす影響－自発運動リズム・飲水リズムの検出手法の検討－

タイトル（英文）

THE BIOLOGICAL EFFECT OF ELECTRIC FIELDS ON LABORATORY ANIMALS -EXPERIMENTAL APPROACH TO DETECT THE DAILY PATTERNS OF MOTOR ACTIVITY AND DRINKING OF MICE-

概要 （図表や脚注は「報告書全文」に掲載しております）

電界が動物のバイオリズムに及ぼす影響を明らかにするための一つの方法として動物の自発運動，飲水，摂餌などの基本的な情報を検出する必要が考えられる。本報告ではマウスの自発運動，飲水の各リズムをカップ状金属ケージ内で検出する実験的手法の検討結果を述べている。

概要 （英文）

WE ASK WHETHER THE CIRCADIAN RHYTHM SHOWS ANY DIFFERENCE UNDER AC ELECTRIC FIELDS.FOR THIS PURPOSE,IT IS NECESSARY TO MEASURE AUTOMATICALLY THE REGULARITY OF ANIMAL ACTIVITY. IN THIS PAPER,WE SHOW THE DRINKING AND MOTOR ACTIVITY PATTERNS IN MICE UNDER 12:12LIGHT-DARK CYCLES IN ANIMAL CAGE WHICH ARE USED FOR EXPOSURE OF AC ELECTRIC FIELDS.FOR THE DETECTION OF DRINKING PATTERNS,THE COMMERCIAL TYPEINSTRUMENT WAS APPLIED SO AS TO SUIT FOR OUR STUDY.FORTHE DETECTION OFMOTOR ACTIVITY,A SIMPLE INSTRUMENT WAS NEWLY DEVELOPED,WHICH IS BASED ON THE PRINCIPLE OF LIGHT-BEAM METHOD.THE ACTIVITY PATTERNS WAS DETERMINED COUNTING THE NUMBER OF BEAM INTERRUPTIONS PER GIVEN TIME PERIOD.DRINKING AND MOTOR ACTIVITY PATTERNS SYNCHRONIZED WITH LIGHT-DARK ALTERNATION. FROM THESE RESULTS,WE CONCLUDED THAT OUR NEWLY DEVELOPED SYSTEM ISSUITABLE FOR THE STUDY OF CIRCADIAN RHYTHMS OF DRINKING AND MOTOR ACTIVITY UNDER AC ELECTRICFIELDS.

報告者

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